One-Pot Cajun Chicken Alfredo

Featured in: Comfort Cravings

This one-pot dish combines tender chicken with al dente orzo pasta, enveloped in a luscious Cajun Alfredo sauce. Layers of smoked paprika and Cajun seasoning add a zesty kick to the creamy Parmesan-infused sauce. It’s prepared quickly by searing chicken, sautéing aromatics, and simmering the pasta in seasoned broth before folding in cream and cheese. Finished with fresh parsley, it's perfect for busy evenings seeking bold, comforting flavors without fuss.

Updated on Sun, 23 Nov 2025 16:29:00 GMT
One-Pot Cajun Chicken Alfredo Orzo, a creamy, savory skillet meal with tender chicken and fluffy orzo. Save
One-Pot Cajun Chicken Alfredo Orzo, a creamy, savory skillet meal with tender chicken and fluffy orzo. | sugarprairie.com

A quick and creamy one-pot meal that blends tender chicken, al dente orzo, and a zesty Cajun Alfredo sauce. Perfect for busy weeknights, this dish delivers bold flavors and comforting richness in just 30 minutes.

I first served this to my family on a hectic weeknight, and the quick preparation along with the bold Cajun flavors made it an instant favorite.

Ingredients

  • Chicken: 1 lb (450 g) chicken breast, diced (substitute with shrimp or Andouille sausage if desired), Salt and black pepper to taste
  • Spice Blend: 1 tbsp Cajun seasoning (adjust for spice preference), 1 tsp smoked paprika (regular paprika can be used), 1/4 tsp red pepper flakes (optional for extra heat)
  • Base: 2 tbsp olive oil, 2 tbsp butter, 1 medium onion chopped (yellow or sweet preferred), 3 cloves garlic minced
  • Pasta: 1 cup (190 g) orzo pasta (substitute with other small pasta if needed)
  • Sauce: 2 cups (480 ml) low-sodium chicken broth, 1 cup (240 ml) heavy cream (or half and half for a lighter version), 1 cup (90 g) Parmesan cheese freshly grated
  • Garnish: 1 tbsp fresh parsley chopped

Instructions

Step 1:
Heat olive oil and butter in a large skillet over medium-high heat. Add diced chicken, season with salt and pepper, and sear for 3 4 minutes until golden brown. Remove chicken and set aside.
Step 2:
In the same skillet, add chopped onion and sauté for 2 3 minutes until translucent. Stir in minced garlic and cook for 1 minute until fragrant.
Step 3:
Add orzo pasta to the skillet, stirring to combine. Toast for 1 2 minutes until lightly golden.
Step 4:
Pour in chicken broth and sprinkle in Cajun seasoning, smoked paprika, and red pepper flakes. Stir well, bring to a boil, then reduce heat to low. Cover and simmer for 10 12 minutes, stirring occasionally, until orzo is al dente and most of the liquid is absorbed.
Step 5:
Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until the sauce is creamy and smooth.
Step 6:
Return the cooked chicken to the skillet and stir to combine. Heat through for 1 minute. Taste and adjust seasoning as needed.
Step 7:
Garnish with fresh parsley before serving.
Golden chicken and al dente orzo swim in a flavorful Cajun Alfredo sauce in this one-pot meal. Save
Golden chicken and al dente orzo swim in a flavorful Cajun Alfredo sauce in this one-pot meal. | sugarprairie.com

This recipe has become a go-to for busy weeknights and a favorite for sharing family meals full of warmth and flavor.

Notes

For extra vegetables and color, add bell peppers or spinach. Serve with crusty bread or a green salad. Pairs well with a chilled Sauvignon Blanc or light lager.

Tools You Need

Large skillet with lid, wooden spoon or spatula, chef's knife, cutting board, measuring cups and spoons, grater for Parmesan cheese.

Allergen Information

Contains dairy (butter, cream, Parmesan cheese) and gluten (orzo pasta). May contain traces of other allergens; always check ingredient labels if sensitivity is a concern.

Garnish a bowl of One-Pot Cajun Chicken Alfredo Orzo with fresh parsley; the ultimate comfort food. Save
Garnish a bowl of One-Pot Cajun Chicken Alfredo Orzo with fresh parsley; the ultimate comfort food. | sugarprairie.com

This creamy Cajun Alfredo orzo is sure to delight your taste buds, making weeknight dinners easier and more delicious than ever.

Kitchen Help

Can I substitute the chicken with other proteins?

Yes, shrimp or Andouille sausage can replace chicken, though cooking times may vary slightly.

How do I adjust the spice level of this dish?

Modify the amount of Cajun seasoning and red pepper flakes to suit your preferred heat level.

What is the best way to ensure the orzo is perfectly cooked?

Simmer the orzo in the seasoned broth until al dente, stirring occasionally to prevent sticking.

Can I make this dish lighter?

Use half and half instead of heavy cream and slightly reduce the Parmesan cheese for a lighter version.

What sides pair well with this creamy dish?

Serve with crusty bread or a fresh green salad to balance the richness and enhance the meal.

Is it possible to add vegetables?

Yes, adding bell peppers or spinach during the sauté step adds color and extra nutrients.

One-Pot Cajun Chicken Alfredo

Creamy chicken and orzo melded with bold Cajun spices for a quick, comforting meal.

Setup duration
10 min
Heat duration
20 min
Complete duration
30 min
Created by Molly Evans

Classification Comfort Cravings

Complexity Easy

Heritage Cajun

Output 4 Portions

Nutrition guidelines None specified

Components

Chicken

01 1 lb diced chicken breast
02 Salt, to taste
03 Black pepper, to taste

Spice Blend

01 1 tbsp Cajun seasoning
02 1 tsp smoked paprika
03 1/4 tsp red pepper flakes (optional)

Base

01 2 tbsp olive oil
02 2 tbsp unsalted butter
03 1 medium onion, chopped
04 3 cloves garlic, minced

Pasta

01 1 cup orzo pasta

Sauce

01 2 cups low-sodium chicken broth
02 1 cup heavy cream
03 1 cup freshly grated Parmesan cheese

Garnish

01 1 tbsp fresh parsley, chopped

Method steps

Phase 01

Sear chicken: Heat olive oil and butter in a large skillet over medium-high heat. Season diced chicken with salt and pepper, then sear for 3 to 4 minutes until golden brown. Remove chicken and set aside.

Phase 02

Sauté aromatics: In the same skillet, add chopped onion and cook for 2 to 3 minutes until translucent. Stir in minced garlic and cook for an additional minute until fragrant.

Phase 03

Toast orzo: Add orzo pasta to the skillet and stir to combine. Toast for 1 to 2 minutes until lightly golden.

Phase 04

Simmer orzo with spices: Pour in chicken broth, then sprinkle Cajun seasoning, smoked paprika, and red pepper flakes. Stir well, bring to a boil, reduce heat to low, cover, and simmer for 10 to 12 minutes, stirring occasionally, until orzo is al dente and most liquid is absorbed.

Phase 05

Incorporate cream and cheese: Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until sauce is creamy and smooth.

Phase 06

Combine chicken and finish: Return cooked chicken to skillet and stir to combine. Heat through for 1 minute. Adjust seasoning if needed.

Phase 07

Garnish and serve: Sprinkle fresh parsley over the dish before serving.

Kitchen tools needed

  • Large skillet with lid
  • Wooden spoon or spatula
  • Chef's knife
  • Cutting board
  • Measuring cups and spoons
  • Grater for Parmesan cheese

Dietary concerns

Review ingredients carefully for potential allergens and seek professional medical guidance if uncertain.
  • Contains dairy and gluten

Dietary breakdown (per portion)

Values shown are estimates only - consult healthcare providers for specific advice.
  • Energy: 560
  • Fats: 28 g
  • Carbohydrates: 45 g
  • Proteins: 35 g